Ferritin+ Delayed-Release Iron Supplement bottle and capsules Ferritin+ Delayed-Release Iron Supplement bottle and capsules

Ferritin+®

A Revolutionary Breakthrough
in Iron Supplementation

Flora’s Ferritin+® is a novel iron supplement
that merges simple, organic ingredients with the best
in scientific innovation, with astounding results.

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100% Plant-Based Iron
Gentle Delayed-Release for Comfort
Unique Absorption Pathway
Supported by Research
Award-winning Iron Supplement

What is ferritin?

Ferritin is a protein that our bodies use as an iron storage mechanism. When needed, ferritin-held iron is readily incorporated into human or animal red blood cells or used to create hemoglobin. Until then, ferritin essentially forms a protective forcefield around iron mineral atoms which can otherwise be reactive ions. This serves to protect both the iron (from oxidizing), and the body’s tissues (from free radical damage caused by oxidation).

Research into ferritin has intensified in the past 40 years, but research into the bioavailability of ferritin from plant-based sources was not studied until the early 2000s. Ferritin is an iron-holding compound and normally filled with iron, but when found without iron, ferritin protein is called apo-ferritin.

Ferritin+® Introduces a Groundbreaking Approach to Iron Supplementation

Ferritin+ uses a VIP entrance. Most minerals compete for absorption in the duodenum, where our body plays a passive role. Using ferritin in an iron delivery system is an advanced technique that makes it possible to use a previously inaccessible, but highly superior, route of absorption. For this reason, research indicates that ferritin iron might be effective in treating iron deficiencies previously refractive to the usual iron treatments.

The Easiest Way to Build Iron
  • Easy on your stomach – minimize digestive distress
  • Easy for your body to absorb – unique absorption mechanism efficiently delivers iron right where your body needs it, when it needs it
  • Easy to take – just 1 capsule per day
  • Easy 20 mg of elemental iron per dose

Finally, an iron supplement that’s Easy to take everyday

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The Science Behind Ferritin+®

Heme iron, iron salts and ferritin iron enter enterocytes by different mechanisms. Ferritin was expected to be digested in the gastrointestinal tract and taken from the iron mineral, but this turned out to be false. Ferritin is barely affected by pepsin and pancreatin.

Ferritin+ uses ferritin protein to shuttle thousands of iron atoms into cells. Uptake of the ferritin-held iron relies on receptor-mediated endocytosis, an existing body mechanism used for absorption of ferritin produced endogenously. The body controls the absorption process in the lumen through endothelial cell receptors.

Ferritin molecules fit perfectly into these receptors which recognize them and grant access to them and the iron they contain. Iron in ferritin is absorbed as an intact protein-iron complex. Once a ferritin molecule is docked in a receptor, the cell enrobes it with a protein called clathrin, then slowly dissolves the ferritin to gradually release the iron inside.

Why Ferritin+® is the Smart Choice

Ferritin+ offers several advantages over traditional iron supplements.

Improved Compliance

Ferritin+ addresses the common issues of poor compliance associated with traditional iron supplements, such as complex dosing schedules and side effects like constipation. Its user-friendly design and minimal side effects make it easier for patients to adhere to their iron supplementation regimen.

Safety Profile

Ferritin+ releases iron gradually, reducing the risk of oxidative damage to intestinal cells. Research has shown that its absorption is regulated based on the patient's iron deficiency levels, minimizing the risk of iron overload in individuals with adequate iron status.

Medication Compatibility

Since Ferritin+ does not rely on absorption in the duodenum, it is a safer option for patients on critical medication regimens, reducing potential interference with other treatments.

Enhanced Absorption

Unlike conventional iron supplements that often compete for absorption in the duodenum, Ferritin+ uses an innovative absorption route that bypasses this competition. This approach leverages receptor-mediated endocytosis, a mechanism utilized by the body to absorb ferritin endogenously, enabling a more effective iron uptake.

Your Patients Will Love Ferritin+®

Simplified Dosage for Busy Lifestyles

Ferritin+ delivers 20 mg of elemental iron in one easy-to-take capsule per day, seamlessly fitting into patients' daily routines without the need for additional co-factors like vitamin C.

Overcome Dietary Obstacles to Iron Absorption

Unlike typical iron supplements, Ferritin+ is impervious to various dietary inhibitors. Iron is effectively absorbed even in the presence of phytates, oxalates, tannins, and calcium, eliminating the need for dietary changes. This simplicity enhances the flexibility of iron supplementation and is great for patients who love their whole grains, leafy greens, or coffee.

Gentle Delayed-Release for Comfort

The ferritin protein in Ferritin+ acts as a protective 'cage', allowing for slow release over time, helping to maintain healthy iron levels without oxidative damage or irritation to the intestinal lining. This minimizes digestive distress like constipation, a common side effect of typical iron supplements, by allowing iron to move gently through the digestive tract.

100% Plant-Based Iron

Ferritin+ is suitable for vegans and those with gluten sensitivities, making it an inclusive option for a wide range of dietary needs.

Frequently Asked Questions

Ferritin+ is said to be the easiest iron supplement. Why is that?

Many patients with low iron levels require other nutrients, too. However, iron usually competes with calcium and other nutrients, reducing overall nutrient absorption and making it difficult to treat concurrent mineral deficiencies successfully. This competition poses a problem for those who are pregnant, for those with malabsorption, short bowel syndrome, Crohn’s, or celiac disease, or for seniors, vegetarians, or others who include calcium-rich dairy products to meet their protein and calorie needs. The iron in Ferritin+, however, does not compete with minerals and is not absorbed alongside them in the digestive tract, making life easier. It is also unbothered by heat, pH, and protein denaturants.

I tell patients to avoid coffee when taking iron. Does that apply to Ferritin+?

Common forms of iron are bound by the tannins in popular beverages. A study showed that drinking coffee within two hours of taking an iron supplement reduced iron absorption by 80%. However, ferritin is unaffected by dietary tannins, as shown in a clinical study. Therefore, Ferritin+ is the best choice for patients who are regular consumers of coffee and tea, and possibly wine.

Many otherwise healthy patients have difficulty increasing their iron levels, especially those following special eating plans. Would Ferritin+ make a difference?

Ferritin+ pairs easily with any eating regimen. Its iron appears very bioavailable and well-absorbed even when a diet is high in phytate, making life easier for anyone on a plant-based, whole food, or high-fiber diet. Other forms of iron can be bound up or blocked by many healthy foods high in dietary oxalates or phytates, such as dark leafy greens, whole grains, nuts, seeds, legumes, and some vegetables. Ferritin+ gives people following paleo, Whole 30, keto, and other diets more flexibility and allows increases in fiber to prevent constipation, something many pregnant patients consider non-negotiable.

I see your product provides 20 mg of elemental iron daily. My clients are frequently anemic and need higher doses of iron. Can your product still help?

Yes. The amount per capsule covers the Recommended Daily Intake to prevent deficiency in the general population. However, practitioners can suggest two capsules daily for symptomatic patients, as this is still within the safe limit for daily iron supplementation for those without a blood test. For those who have tested as deficient or anemic, licensed/prescribing practitioners can request patients take three Ferritin+ capsules daily or 60 mg of iron daily.

What would you suggest for a patient who must significantly raise their serum iron as quickly as possible due to an upcoming surgery?

To maximize all available absorption pathways, they may combine Ferritin+ capsules with other iron types, such as an iron salt and a heme source. A study checked if ferrous sulfate would compete with the ferritin, and up to 50 mg of ferrous sulfate did not affect the absorption of ferritin. Similarly, adding hemoglobin/heme iron did not lower the uptake of ferritin. Checks to see if it would compete with ferritin showed an impact only once the heme Fe: ferritin Fe ratio was 19:1.

Click here to read more about clinical studies relevant to Ferritin+